# Chemgenes Corporation, a DNA RNA Biotechnology company

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- About us
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  - What We Do
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- Oligonucleotide Synthesis Reagents
  - DNA
  - Amidites (P-O-Cyanoethyl) & Supports
  - Amidites (P-O-Methox) & Supports
  - (P-O-Benzyl) Phosphoramidites
  - Amidites (P-O-Ethoxy) & Supports
  - Alpha DNA Amidites
  - Photocleavable (5’-NPPOC) Amidites
  - Reverse DNA Synthesis
  - Non-Cleavable Supports
  - 5’-Levuinyl Protected Amidites
  - Dimer Phosphoramidites
  - H-Phosphonate Monomers
  - RNA
  - Amidites (P-O-Cyanoethyl) & Supports
  - Amidites (P-O-Methoxy) & Supports
  - Reverse RNA Synthesis
  - Unnatural 2’-5’ Linked RNA
  - Antisense
  - 2’-O-Methyl (P-O-Cyanoethyl) & Supports
  - 2’-O-Methyl (P-O-Ethoxy) & Supports
  - 2’-O-Methyl P-Methyl Phosphonamidites
  - 3’-O-Methyl Amidites and Supports
  - Reverse 2’-O-Methyl Amidites and Supports
  - 2’-O-Deoxy Amidites (P-O-Ethoxy) & Supports
  - 2’-O-Deoxy (P-O-Methoxy) Amidites
  - 2’-O-Deoxy (P-O-isoPropoxy) Amidites
  - 2’-O-Deoxy P-Methyl Phosphonamidites
  - 2’-O-Butyne Amidites and Supports
  - 2’-O-Propargyl Amidites and Supports
  - 3’-O-Propargyl Amidites and Supports
- Nucleosides, Protected Nucleosides
  - Unprotected Nucleosides
  - N-protected Nucleosides
  - DMT-protected Nucleosides
- Specialty Oligonuclotides Synthesis
- Triphosphates

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### Base Modifications

1. 2-thio & 4-thio
2. isoC and isoG
3. 4-Triazolyl - Convertible Bases
4. deoxy Inosine & deox uridine
5. alpha DNA Amidites
6. 3’-Amino & 5’ Amino
7. 2’-trifluoroacetamido-propyl
8. Arabanoside
9. 3’-deoxy Adenosine (Cordecypin)
10. 7-deaza Modifications
11. 7-deaza-7-Iodo Modification
12. 5-methyl cytidine & N-Alkylated
13. 2-aminopurine, nebuylarine, etc.
14. Halogenated Bases, ie 5-iodo-dU
15. Abasic and everse Abasic
16. dideoxy
17. 8-oxo

### Ancillary Reagents

1. Acetonitrile, Wash grade
2. Acetonitrile, Amidite Diluent
3. Activator Solutions
4. Deblock Solutions
5. Capping Reagents
6. Oxidation & Sulfurizing Reagents
7. Drying traps (Moisture Traps)

### Attachment Chemistry

1. 5’-Phosphorylation
2. Fluorophore Amidites & Supports
3. Reporters
4. Quenchers
5. Linker & Spacer Amidites & Supports
6. Branching amidites & Supports
7. Cross-Linking Amidites & supports

Oligonucleotied Purification

### ABOUT US: Our Place in the Biotechnology Industry

ChemGenes Corporation, a biotechnology company, recently relocated to a state of the art facility in Wilmington, Massachusetts. We have consistently been a strong partner to researchers engaged in the field of DNA/RNA synthesis for 23 years. By starting out as a supplier of ‘Ultra Pure Products’ and then also by becoming and active Contract Researcher, ChemGenes Corporation has achieved unparalled expertise in the field of DNA/RNA synthesis. Thus, all of us at ChemGenes have the opportunity and great pleasure to serve a vast number of scientists in the US and all over the world.
ChemGenes’ product lines include phosphoramidites for RNA and DNA synthesis, Antisense phosphoramidites, modified bases for DNA, as well as RNA modification. In addition, we produce a variety of modified phosphoramidites for the introduction of chromophores and ligands. The availability of prepacked disposable columns of various pore sizes, loadings, low volume columns, ancillary reagents in configurations suitable for each synthesizer, and DNA purification cartridges is another way ChemGenes meets its customers needs.
A large variety of Reagents for the synthesis of DNA/RNA are also available, which include many natural and modified nucleoside bases, tetrazole, 5-thioethyltetrazole, DMT-chloride, DMT protected deoxy and ribo nucleosides, 2’-O-methyl and 2’-O-propargyl nucleosides, silyl protected ribonucleosides, several types of phosphorylating reagents, and many more.
As the market for oligonucleotides continues to grow, ChemGenes will stay committed to introducing novel products, while maintaining its existing product mix. We also have the capacity to custom synthesize products on request. Our highly trained technical staff is always available and happy to help you with your special needs and demands in this area. For information regard the full range of products and their applications, please call us at 800-762-9323.